Kenneth D R Setchell Selected Research

Liver Diseases (Liver Disease)

3/2023	Essential Fatty Acid Deficiency Associates with Growth Faltering and Environmental Enteric Dysfunction in Children.
1/2023	Innate immune cell dysfunction and systemic inflammation in children with chronic liver diseases undergoing transplantation.
1/2023	Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy.
12/2022	Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis.
10/2021	Genetic spectrum and clinical characteristics of 3β-hydroxy-Δ5-C27-steroid oxidoreductase (HSD3B7) deficiency in China.
4/2021	Successful treatment of infantile oxysterol 7α-hydroxylase deficiency with oral chenodeoxycholic acid.
11/2018	Inborn Errors of Bile Acid Metabolism.
5/2018	Long-Term Cholic Acid Therapy in Zellweger Spectrum Disorders.
12/2017	Bile Acid Synthesis Disorders in Arabs: A 10-year Screening Study.
1/2017	Oral Cholic Acid Is Efficacious and Well Tolerated in Patients With Bile Acid Synthesis and Zellweger Spectrum Disorders.

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Kenneth D R Setchell Research Topics

Disease

26	Liver Diseases (Liver Disease) 03/2023 - 08/2002
20	Cholestasis 01/2023 - 08/2002
19	Gaucher Disease (Gaucher's Disease) 01/2023 - 01/2011
9	Inflammation (Inflammations) 11/2023 - 06/2004
7	Zellweger Syndrome (Zellweger's Syndrome) 01/2020 - 01/2003
5	Neoplasms (Cancer) 01/2023 - 01/2002
5	Liver Failure 01/2023 - 12/2017
4	Infections 01/2023 - 10/2015
4	progressive familial intrahepatic 1 Cholestasis 10/2022 - 10/2003
4	Pruritus (Itching) 10/2022 - 10/2003
4	Intrahepatic Cholestasis 01/2022 - 10/2003
4	Body Weight (Weight, Body) 01/2020 - 10/2005
4	Lysosomal Storage Diseases (Lysosomal Storage Disease) 12/2018 - 01/2014
3	Type 2 Diabetes Mellitus (MODY) 01/2024 - 09/2011
3	Lung Diseases (Lung Disease) 01/2023 - 02/2015
3	Biliary Atresia 01/2023 - 01/2017
3	Sclerosing Cholangitis 12/2022 - 02/2016
3	Liver Cirrhosis (Hepatic Cirrhosis) 10/2021 - 01/2015
3	Cystic Fibrosis (Mucoviscidosis) 01/2020 - 06/2004
3	Fibrosis (Cirrhosis) 01/2017 - 06/2004
3	Osteoporosis 03/2015 - 08/2004
3	Cardiovascular Diseases (Cardiovascular Disease) 03/2015 - 12/2004
3	Alzheimer Disease (Alzheimer's Disease) 01/2015 - 01/2002
3	Breast Neoplasms (Breast Cancer) 11/2011 - 05/2010
2	Malnutrition (Nutritional Deficiencies) 03/2023 - 01/2019
2	Hot Flashes 01/2023 - 03/2015
2	Disease Progression 12/2022 - 09/2017
2	Alagille Syndrome (Alagille-Watson Syndrome) 10/2022 - 10/2021
2	Pain (Aches) 10/2020 - 01/2020
2	Weight Gain 02/2019 - 01/2003
2	Weight Loss (Weight Reduction) 11/2016 - 01/2015
2	Fatty Liver 01/2016 - 01/2015
2	Non-alcoholic Fatty Liver Disease 01/2016 - 11/2014
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2015 - 08/2014
2	Obesity 01/2015 - 09/2010
2	Hyperplasia 07/2011 - 10/2010
2	Adrenal hyperplasia 2 10/2009 - 04/2003
1	Graft vs Host Disease (Graft-Versus-Host Disease) 02/2024
1	Bronchiolitis Obliterans Syndrome 02/2024
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2024
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2024
1	Neurologic Manifestations (Neurological Manifestations) 01/2023
1	Parkinson Disease (Parkinson's Disease) 01/2023
1	Hemolytic Anemia 01/2023
1	Tuberous Sclerosis (Bourneville's Disease) 01/2023
1	Cystadenoma 01/2023

Drug/Important Bio-Agent (IBA)

36	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 01/2003
15	AcidsIBA 11/2023 - 01/2003
13	IsoflavonesIBA 01/2015 - 01/2002
10	GlucosidasesIBA 01/2019 - 04/2011
9	LipidsIBA 11/2023 - 04/2003
9	Biomarkers (Surrogate Marker)IBA 03/2023 - 10/2010
8	EnzymesIBA 01/2020 - 07/2006
8	Cholic AcidIBA 01/2020 - 06/2004
7	Glucosylceramides (Glucocerebrosides)IBA 09/2017 - 01/2011
6	sphingosyl beta-glucosideIBA 09/2017 - 04/2011
6	VitaminsIBA 01/2015 - 01/2003
5	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 02/2017 - 06/2004
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2007
4	Oxidoreductases (Dehydrogenase)IBA 10/2021 - 04/2003
4	EquolIBA 03/2015 - 10/2007
4	Hormones (Hormone)IBA 10/2005 - 01/2002
4	Phytoestrogens (Phytoestrogen)IBA 04/2005 - 01/2002
3	BilirubinIBA 01/2023 - 01/2017
3	Glucosylceramidase (Glucocerebrosidase)IBA 01/2023 - 01/2011
3	maralixibatIBA 10/2022 - 10/2021
3	Arginine (L-Arginine)FDA Link 01/2022 - 10/2015
3	GlycosphingolipidsIBA 01/2018 - 01/2014
2	SphingolipidsIBA 01/2024 - 01/2023
2	Morphine (MS Contin)FDA LinkGeneric 10/2020 - 01/2020
2	Vitamin D FDA LinkGeneric 02/2019 - 01/2003
2	SaposinsIBA 01/2019 - 04/2011
2	CitrullineIBA 01/2019 - 10/2015
2	Lysergic Acid Diethylamide (LSD)IBA 12/2018 - 08/2014
2	ProgranulinsIBA 12/2018 - 11/2016
2	GangliosidesIBA 01/2018 - 12/2017
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2017 - 02/2016
2	CholesterolIBA 01/2016 - 09/2005
2	UbiquitinIBA 02/2015 - 08/2014
2	LignansIBA 03/2014 - 10/2010
2	SterolsIBA 10/2013 - 07/2004
2	isofagomineIBA 02/2012 - 04/2011
2	daidzeinIBA 01/2006 - 01/2003
2	GenisteinIBA 01/2006 - 01/2003
1	ruxolitinibIBA 02/2024
1	SteroidsIBA 02/2024
1	CreatinineIBA 01/2024
1	Nonesterified Fatty Acids (NEFA)IBA 03/2023
1	Fatty Acids (Saturated Fatty Acids)IBA 03/2023
1	lipoarabinomannan (LAM)IBA 01/2023
1	AntigensIBA 01/2023
1	trans-sodium crocetinate (crocetin)IBA 01/2023
1	Interleukin-12 (IL 12)IBA 01/2023
1	Sirolimus (Rapamycin)FDA Link 01/2023

Therapy/Procedure

14	Therapeutics 12/2022 - 01/2003
4	Liver Transplantation 12/2017 - 01/2003
2	Transplantation 01/2023 - 10/2022
2	Gastrectomy 11/2016 - 11/2014
1	Vegan Diet (Diet, Vegan) 01/2023
1	Ambulatory Care (Outpatient Care) 01/2023